The Oti Region is one of the six newly created regions in Ghana in December 2018 by the New Patriotic Party under H.E. President Nana Addo Dankwa Akufo-Addo.

It’s located to the north of the Volta region. The distance between Accra and Oti Region is 263 km. The road distance is 554.4 km.

The Oti Region is made up of eight (8) Municipal and District Assemblies (MDAs) under its jurisdiction, namely, Krachi East Municipal with its capital as Dambai, Kadjebi District which has Kadjebi as the capital, Jasikan District with Jasikan being the capital, Nkwanta North District also has its capital as Kpasa, Nkwanta South Municipal with Nkwanta as the capital, Krachi Nchumuru with Chineden as its capital, Biakoye District with its capital as Nkonya Ahenkro, Krachi West District with Kete Krachi as the capital.

The Region is host to amazing tourist sites such as the Kyabobo National Park which has the Breast Mountains, Lake Volta, Chaiso Forest Reserve, Hanging Village, Shiare, and a few more that are yet to be discovered.

There are several ethnic groups in the Oti Region. Evidence of this is visible in how its capital city, Dambai is made up.

The tribes that can be found in Dambai include the Nchumuru, Zabarama, Hausa, Kotokoli, Ewe, Konkonba, Basari, Ada, and the Fulani. As a result of this, the languages spoken in Oti Region vary widely.

The Oti–Volta languages form a subgroup of the Gur languages, comprising about 30 languages of northern Ghana, Benin, and Burkina Faso spoken by twelve million people. The most populous language is Mõõré, the national language of Burkina, spoken by five million people.

The Akwantutenten Festival is an annual festival celebrated by the chiefs and peoples of Worawora in the Jasikan District in the Oti Region of Ghana formally the Volta region who are Akans. It is usually celebrated in September.